T Cell Receptor Signaling That Regulates the Development of Intrathymic Natural Regulatory T Cells
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چکیده
منابع مشابه
T Cell Receptor Signaling That Regulates the Development of Intrathymic Natural Regulatory T Cells
T cell receptor (TCR) signaling plays a critical role in T cell development, survival and differentiation. In the thymus, quantitative and/or qualitative differences in TCR signaling determine the fate of developing thymocytes and lead to positive and negative selection. Recently, it has been suggested that self-reactive T cells, escape from negative selection, should be suppressed in the perip...
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ژورنال
عنوان ژورنال: Immune Network
سال: 2011
ISSN: 1598-2629,2092-6685
DOI: 10.4110/in.2011.11.6.336